The Courchet Lab

The team of Vincent Gache from INMG just recently posted a new preprint studying the roles of the microtubule binding protein MACF1 in myofiber’s nuclei positioning. Myofibers (the cells of the muscles) are weird cells with lots of nuclei. They have to be at the periphery so the fiber remains healthy. This protein MACF1 helps…

The registrations are now open for the 10th Imaging the Cell meeting, which will take place in Lyon on November 4-6th, 2019. This meeting will cover the most recent conceptual and technological advances in cell imaging at both cellular and ultrastructural levels, featuring talks from invited and selected speakers. The afternoon will be dedicated to…

Our little lab is growing. This January we have the privilege to welcome three new lab members: Evelyne Goillot, CNRS research director with expertise in cell signaling Louise Fairey, Master 2 student in physiology Luc Javin, Master 1 student in cell biology

Our latest research is now published in the journal Nature Communications and is accessible as an open access manuscript! Loss of one allele of NUAK1 disrupts brain development in the mouse. One of the main phenotype is an enlargment of the lateral ventricles (visible on the right) with a corresponding thinning of the cortex.  The…

The Courchet team has been awarded a 20,000€ research grant from the Neurodis foundation to study the alterations of mouse cognition and neural circuits formation resulting from mutation in the Nuak1 gene. The projet will continue our work on the characterization of the functional consequences of Nuak1 gene mutations associated to neurodevelopmental disorders and will…

Notre équipe recrute pour l’année 2018-2019 deux étudiants en Master 2 pour des projets de recherche visant à identifier les fonctions cellulaires de la kinase NUAK1 dans un contexte sain et pathologique. Les projets proposés pourront déboucher sur une offre de thèse.

Our latest study has been deposited as a preprint on bioRxiv. This is work started in the Polleux laboratory and focusing on the relevance of mutations in the Nuak1 gene for the neurodevelopment in mouse models. Work by Virginie Courchet from the team & in collaboration with Amanda J Roberts from the Scripps Institute. Check…

After a 2 year stay on the science campus in Villeurbanne, our lab moved to a brand new lab space on the Rockefeller medical campus in Lyon. We are now all settled in & ready to do good science.